Correction: Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients
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چکیده
There are errors in the Funding section. The correct funding information is as follows: This work was funded by the Muscular Dystrophy Association of USA (MDA), the Fight-MG grant of the FP7 EC program, the Association Francaise contre les Myopathies (AFM), the European Commission (Contract No 242210), the Greek GSRT (program “Aristeia”), FP-7 Research potential Program/Regpot SEEDRUG of University of Patras (Grant number: EU FP7 REGPOT CT-2011-285950) and by the Greek national funds through the Operational Program “Education and Lifelong Learning” of the National Strategic Reference Framework (NSRF) Research Funding Program: THALES. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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Thymolipoma-associated Myasthenia Gravis with High Titer of Anti-MuSKAb: A Case Report
Myasthenia Gravis (MG) is a neuromuscular junction disorder caused by pathogenic autoantibodies to some parts of the post-synaptic muscle endplates. About 85% of generalized MG patients have autoantibodies against post-synaptic acetyl-choline receptors (AChR). From the 10-15% of the remaining patients, 45-50% are positive for Muscle Specific Tyrosine Kinase-Antibody (MuSK-Ab). It is believed th...
متن کاملCorrection: Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients
Several studies have suggested that the autoantibodies (autoAbs) against muscle acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic factor in MG; however, this belief has not yet been confirmed with direct observations. Although animals immunized with AChR or injected with anti-AChR monoclonal Abs, or with crude human MG Ig fractions exhibit MG symptoms, the...
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Autoantibodies directed against the skeletal muscle acetylcholine receptor (AChR) play a critical role in the pathogenesis of the autoimmune disease, myasthenia gravis (MG). The pathogenic importance of anti-AChR antibodies is substantiated clinically by the often dramatic clinical improvement that follows removal of circulating antibodies utilizing extracorporeal plasma exchange (PE). Unfortun...
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